Unleash The Power
of Biomanufacturing
We invest in nature's chemistry to disrupt how
people and companies consume products.
Smiles expected, not guaranteed.
Check Out Our Awesome Portfolio Companies
The Most important problem Humans face
Multi Trillion Dollar Industries Are Hunting For Solutions
The largest industries on planet earth are all trying to find sustainable inputs.
$6T+ Chemical Industry
$14T+ Manufacturing Industry
$14T+ Agriculture Industry
$12T+ Construction & Infrastructure Industry
$8T+ Automotive & Transportation Industry
$2.5T+ Textiles & Apparel Industry
Without venture funding to scale nature's chemistry, these sectors will continue to be reliant on commodity materials that require extraction and pollution.
Our goal is to help society transition from a model of extraction, into a model of regeneration.
Let us help you invest in biosolutions!
A Message from...
First Bight Founder & Managing Partner
Hey! My name is Veronica, and I founded First Bight to accelerate societies use of nature's chemistry.
In our first fund, the First Bight team invested in 7 early stage biomanufacturing companies.
My experience over the past 20+ years is focused on scaling innovative industrial processes.
VF Corporation (Board Member)
Capgemini
Tesla
Apple
Motorola
McKinsey
Biology Is Driving
The Next Industrial Revolution
We are building a biomanufacturing ecosystem that makes scientific breakthroughs profitable.
We work with global stakeholders to scale biomanufacturing in local communities.
Investors
Large Corporations
Biomanufacturing Startups
Governments
Universities
Foundations
Beyond Capital
We Partner With Startups To Scale Impact
If you are looking for silent capital, you are in the wrong place.
We Lead Rounds
We write first checks for
seed through series A.
We Take Board Seats
We are actively involved in
strategy and governance.
We Make Introductions
We leverage our relationships to drive meaningful partnerships.
We Drive Efficiencies
We help our portfolio companies proficiently scale operations.
We Mitigate Risks
We identify and reduce scale up risks to increase shareholder value.
We Love Science
We nerd out on technology
and how it drives impact.
The odds are in our favor
6 Tailwinds Driving Adoption
We are investing in solutions that people are begging for now.
Health Conscious Consumers
Growing concern over ingredient safety and toxicity is reshaping purchasing behavior.
Petroleum At A Cost Floor
No more margin to squeeze from fossil-based products leaving an opening for bio.
Governments Support
Regulations are favoring health-forward
and sustainable alternatives.
Corporate Mandates
Industrial sectors are under pressure to cut CO₂ emissions making room for sustainable inputs.
Cost Parity In Sight
AI and ML have cut R&D costs by 99%+ in 20 years, making bio increasingly competitive.
Supply Chain Resiliency
Geopolitical shocks, tariff swings, and scarce critical materials now threaten national security.
TESTIMONIALS
Why Work With Us?
We have created the leading biomanufacturing venture ecosystem.
"First Bight turns lab scale into industrial powerhouses."
“Veronica & the team dive in early, bring Tesla-level technical rigor, and help founders de-risk scale-up so their companies can print cash.”
- Dave McClure, Founder @ 500 Startups
"Preventing health problems before they pop up."
“By replacing petro-derived inputs with bio-made alternatives, First Bight shifts the focus from costly treatment to proactive prevention."
- Alan McCollough, Fmr Board @ Goodyear
“First Bight knows how to derisk industrial biotech investments.”
“In a complex, long gestation and capital-intensive space, First Bight stands out for how it actively drives progress; not just funds it.”
- Mario Maia, Ventures @ Novozymes
Smiles expected, not guaranteed.
Get behind the scenes
If You're Wondering Why
Smiles expected, not guaranteed.
How To Bio?
Scaling Sustainable Chemistry
We have tailored our approach specifically to support scale up challenges in biomanufacturing.
This laser focus helps startups, investors, corporates, and communities reap the rewards of First Bight's ecosystem.
If you are interested in investing in or scaling sustainable chemicals, please find a time to connect with our team.
Press from port co's
News From Our Portfolio
Stay up to date on advancements from First Bight's portfolio companies.
Persephone
January 23, 2025
Persephone Biosciences Announces First Subject Enrolled in ARTEMIS Clinical Trial of New Infant Synbiotic
Global Newswire
Oct 19, 2023
Persephone Biosciences Announces New Collaboration With Kroger Health to Launch AMBROSIA Food as Medicine Study
BioSpace
Oct 17, 2023
Persephone Biosciences and Ginkgo Bioworks Complete Reusable Bacteroides Anaerobic Engineering Toolkit
Cision
July 27, 2023
Building a Better Microbiome
proto.life
April 27, 2023
“Cancer & the Gut Biome” with Stephanie Culler, Ph.D.
Angel Invest Boston
Jan 24, 2023
Kroger Health Establishes Clinical Trial Site Network to Increase Reach and Access to Research Studies
Cision
Sept 20, 2022
Persephone Biosciences Announces First Participant Enrolled in the ARGONAUT Study of Gut Microbiome-Linked Immune Modulation in Cancer Treatment Response
GlobeNewswire
July 19, 2022
Persephone Biosciences, Pioneers In Synthetic Biology, Lands $15M In Seed Funding
Grit Daily
July 19, 2022
Can bacteria in your gut boost cancer therapies? A San Diego startup thinks so
The San Diego-Union Tribune
July 19, 2022
Persephone puts poop to work to explore and heal your gut microbiome
TechCrunch
Visolis
July 30, 2024
Visolis Receives $2.25M DOD Award to Plan for Domestic Facility
U.S. Dept. of Defense
April 10, 2024
Zeon and Visolis collaborating on commercialization of bio-isoprene monomers
Chemical Engineering
October 26, 2023
Goodyear, Visolis partner for bio-based isoprene
Rubber News
July 20, 2023
Harnessing synthetic biology to make sustainable alternatives to petroleum products
MIT
April 24, 2023
Visolis and Ginkgo Bioworks Announce Partnership to Improve Microbial Strain
Ginkgo Bioworks
Jan 11, 2023
Biomanufacturing Startup Visolis Has Raised $8 Million To Make Carbon-Negative Materials
Forbes
Sept 19, 2019
Visolis Recognized as One of “the 50 Next Companies to Disrupt the World”
The Digest
Algenesis
April 28, 2025
Why Most “Biodegradable” Products Are Probably Fake
Business Insider
February 1, 2025
Flow chemistry yields a more sustainable route to isocyanates
Chemical Engineering Magazine
Sept 16, 2024
DoD Releases 12 Awards for Distributed Bioindustrial Manufacturing Program
June 27, 2024
How Biodegradable Polyurethane Could Solve the Microplastic Pollution Problem
March 24, 2024
May 10, 2023
September 21, 2022
Sustainability Matters: Sanuk Debuts Plant-Based, Carbon-Neutral Sneakers + More News
Footwear News
Capra Biosciences
July 19, 2024
Capra Biosciences Lands $7.5 Million Project Agreement To Demonstrate Platform To Rapidly Scale Pharmaceutical Ingredient Manufacturing
Capra Biosciences
April 29, 2024
How Microbes Are Changing Manufacturing: Why We Invested in Capra Biosciences
Closed Loop Partners
Industrial Microbes
Nov 19, 2024
Industrial Microbes announces seed round funding
iMicrobes Press
Nov 4, 2024
A low-cost method for bio-based production of acrylic acid
Chemical Engineering
September 14, 2023
DoD Releases Seven Awards for Distributed Bioindustrial Manufacturing Program
BioMADE
September 14, 2023
BioMADE Announces Nine Projects, $18.7 Million to Advance Domestic Bioindustrial Manufacturing and DoD Sustainability Goals
BioMADE
R2DIO
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VIA Biofuels
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